KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPKOW
All Species:
13.22
Human Site:
T473
Identified Species:
29.09
UniProt:
Q92917
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92917
NP_056513.2
476
52229
T473
Q
Y
M
G
P
S
D
T
D
D
D
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001141772
224
23867
Rhesus Macaque
Macaca mulatta
XP_001105674
498
55226
T495
Q
Y
M
G
P
S
D
T
D
D
D
_
_
_
_
Dog
Lupus familis
XP_538033
484
53417
S481
Q
Y
M
G
P
S
D
S
D
E
D
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q56A08
488
53813
S485
Q
Y
M
G
P
G
D
S
D
E
D
_
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507594
502
55083
V499
I
C
H
Y
V
G
H
V
D
E
D
_
_
_
_
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU07
487
54677
A484
A
I
C
H
Y
T
G
A
Q
D
D
_
_
_
_
Zebra Danio
Brachydanio rerio
Q90X38
506
57936
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623528
264
29888
Nematode Worm
Caenorhab. elegans
Q21924
462
51694
E459
S
V
K
I
R
H
E
E
D
Y
E
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_780912
479
55253
D475
E
F
A
G
N
L
H
D
E
E
D
Y
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
68.4
80.7
N.A.
74.3
N.A.
N.A.
43.4
N.A.
45.7
44
N.A.
N.A.
24.1
26.2
32.3
Protein Similarity:
100
38.4
73.4
88.6
N.A.
82.5
N.A.
N.A.
56.3
N.A.
61.5
59.2
N.A.
N.A.
39.7
47
53.4
P-Site Identity:
100
0
100
81.8
N.A.
72.7
N.A.
N.A.
18.1
N.A.
18.1
0
N.A.
N.A.
0
9
16.6
P-Site Similarity:
100
0
100
100
N.A.
90.9
N.A.
N.A.
27.2
N.A.
27.2
0
N.A.
N.A.
0
27.2
58.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
37
10
55
28
64
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
10
10
37
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
46
0
19
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
10
0
10
19
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
37
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
28
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
19
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
37
0
10
10
0
0
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
64
73
73
73
% _